X-Nico

unusual facts about Alanine



Mifamurtide

One method of synthesis (shown first) is based on N,N-dicyclohexylcarbodiimide (DCC) assisted esterification of N-acetylmuramyl-L-alanyl-D-isoglutaminyl-L-alanine with N-hydroxysuccinimide, followed by a condensation with 2-aminoethyl-2,3-dipalmitoylglycerylphosphoric acid in triethylamine (Et3N).

Nodaviridae

RNA2 encodes protein α, a viral capsid protein precursor, which is auto-cleaved into two mature proteins, a 38 kDa β protein and a 5 kDa γ protein, at a conserved Asn/Ala site during virus assembly.

Oculopharyngeal muscular dystrophy

This expands the polyalanine tract at the N-terminus of PABPN1 from 10 to 11-17 alanines.


see also