Henry's successor, Isabella and her husband Ferdinand used the Alcázar for one of the first permanent tribunals of the Spanish Inquisition and as a headquarters for their campaign against the Nasrid dynasty in Granada, the last remaining Moorish kingdom in the Iberian Peninsula.
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The Umayyads fell to the Abbasid Caliphate and the surviving member of the Umayyad Dynasty, Abd ar-Rahman I, fled to Córdoba.
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In early medieval times, the site was occupied by a Visigoth fortress.
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