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Henri Poincaré's 1895 paper Analysis Situs studied three-and-higher-dimensional manifolds(which he called "varieties"), giving rigorous definitions of homology, homotopy (which had originally been defined in the context of late nineteenth-century knot theory, developed by Maxwell and others), and Betti numbers and raised a question, today known as the Poincaré conjecture, based his new concept of the fundamental group.