Since the 14th century, Ceri became the property of some of the greatest Italian families: from the Anguillara (of which the greatest exponent was Renzo di Ceri) to Cesi, the Borromeo, the Odescalchi, and ended with the Torlonia, who are still owners of a large part of Ceri.
In the Papal States, however, in 1465 he eliminated the regime of the counts of Anguillara, a house that had played a consistent anti-papal role since the plot of Stefano Porcari and the unruly insurrection of Tiburzio di Maso in 1460.