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In light of his family’s intellectual tradition, he may have been among those Trustees who, following James Oglethorpe, saw the Georgia colony as a potential model society as well as one that addressed several more pragmatic purposes (see the Oglethorpe Plan).
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Shaftesbury was elected to the Trustees for the Establishment of the Colony of Georgia in America in 1733, less than a year after the group was created by royal charter.
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Shaftesbury also commissioned a biography of his great-grandfather, and retained Benjamin Martyn for the project.
Mary Bouverie (2 October 1730 – 12 November 1804), married Anthony Ashley Cooper, 4th Earl of Shaftesbury
The study of Shaftesbury and Bolingbroke wakened his interest in theology, and, breaking off his studies, he set out for Paris.
With the "country party" in disarray, Lord Melville, Lord Leven, and Lord Shaftesbury, leader of the opposition to Charles's rule, fled to Holland where Shaftesbury soon died.
Later in the century Anthony Ashley Cooper, 1st Earl of Shaftesbury, was the target of the four-page political pamphlet Sejanus, or The popular favourite, now in his solitude, and sufferings, signed with the pseudonym Timothy Tory.