Drexel died of a heart attack on June 30, 1893 in Karlsbad (in the German-speaking part of Bohemia, Austrian Empire) today Karlovy Vary, Czech Republic at the age of 66, and was buried in The Woodlands Cemetery in Philadelphia.
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As early as 1915 (in American press reports) and as late as the 1940s (in Nazi broadcasts), she was described as a member of the “famous Drexel family” of Philadelphia, Pennsylvania, an apparent reference to the descendants of Francis Martin Drexel (who founded the Drexel & Company banking empire), including his son Anthony Joseph Drexel (who founded Drexel University in Philadelphia) and his granddaughter Saint Katharine Drexel.
He is a great-great-grandson of banker Anthony Joseph Drexel and a grandson of Ralph Francis Julian Stonor.
Her cousin twice removed, Charles John Biddle, was an aviator in World War I, and great-great-granduncle Edward Biddle (1851–1933) married the daughter of banker Anthony Joseph Drexel.