MotionBuilder is widely used, for example in mainstream products like Assassin's Creed, Killzone 2, and Avatar.
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It is notable for being one of only five pieces of animation software (the other four being Muvizu, Moviestorm, Xtranormal and Autodesk MotionBuilder) that use a real-time "WYSIWYG" view to let animators see the results of their work immediately, and to play back animations in the viewport.