Azide has been used traditionally as an MPO inhibitor, but 4-aminobenzoic acid hydrazide (4-ABH) is a more specific inhibitor of MPO.
Azide |
One such azide reactions is the 3+2 cycloaddition reaction with alkyne, but the reaction requires high temperature and often gives mixtures of regioisomers.
Florian Klepper, Eva-Maria Jahn, Volker Hickmann, Thomas Carell: „Synthesis of the Transfer-RNA Nucleoside Queuosine by Using a Chiral Allyl Azide Intermediate“, Angewandte Chemie International Edition, 2007, 46 (13), pp.
Staudinger reaction, chemical reaction in which the combination of an azide with a phosphine or phosphite produces an iminophosphorane intermediate