In 1961 D. W. Bailey used some of these to generate a substrain at the University of California, San Francisco.
Initially, EuroPhenome was developed within the EUMORPHIA (European Union Mouse Research for Public Health and Industrial Applications) programme to capture and store pilot phenotyping data obtained on four background strains (C57BL/6J, C3H/HeBFeJ, BALB/cByJ and 129/SvPas).