It is specially designed to fit many different types of tracked and wheeled IFVs and APCs such as the BMP-1, BMD-1, BTR-70, BTR-80 and the OT-64 SKOT.
The ZU-23-2 appears in the video games Battlefield: Bad Company, and Battlefield: Bad Company 2 as a towed weapon and also mounted on a variant of the BMD-3.