In contrast, the one of Santo Domingo Soriano, founded with Charrúas and Chanáes in Entre Ríos, Argentina, in 1664, was moved on the Isle of Vizcaíno, on the mouth of Río Negro and then in 1718 it was moved again at its present location in the modern Soriano Department.
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The Portuguese, being able to advance without resistance in the sparsely populated territory, founded the city Colonia del Sacramento on the banks of Rio de la Plata, across from Buenos Aires, in 1680.
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The Portuguese, having lost the possibility of building a fort in Montevideo, established the Fort of San Miguel in 1737 and then the much larger Fortaleza de Santa Teresa in 1762 on the Atlantic coast of the current Rocha Department, in order to keep a route open for their southward advances into the sparsely populated territories of the Banda Oriental.
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The first Federalist leader in the Platine Region was José Gervasio Artigas, who opposed the centralist governments in Buenos Aires that followed the May Revolution, and created instead the Federal League in 1814 among several Argentine Provinces and the Banda Oriental (modern-day Uruguay).
During his rule, Saavedra and Campana were exiled, Montevideo fell to the United Provinces but serious problems arose with José Gervasio Artigas and the Liga Federal on the Banda Oriental.
Ever since colonial times, Portugal has had interests in the Río de la Plata region; its relationship with the Banda Oriental began in 1680, when Colonia del Sacramento was established.