Barbital (as known in the United States) or barbitone (as known elsewhere), marketed under the brand names Veronal for the pure acid and Medinal for the sodium salt, was the first commercially available barbiturate.
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Barbitone was first synthesized in 1902 by German chemists Emil Fischer and Joseph von Mering.
On the night of 7/8 May 1933, Neppach, obviously in despair because of the increasing discrimination and prosecution of Jewish people in Germany and her isolation from tennis in particular, took her life in her flat at Berlin using Barbital and town gas.
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Suffering from severe paranoia due to his use of Veronal as a sleeping aid, he died under mysterious circumstances in his room in the Hotel Seiyoken in Tokyo while visiting colleagues at the University of Tokyo.