He was imprisoned together with Christopher and another brother, Giacomo (also called Diego), by Francisco de Bobadilla and returned to Spain in December 1500.
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Born in the Republic of Genoa, in the 1470s Bartholomew was a mapmaker in Lisbon, the principal center of cartography of the time, and conceived with his brother the "Enterprise of the Indies", a scheme to reach the Orient and its lucrative spice trade by a western rather than an eastern route.
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