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The cartridge was most famously employed by British forces during the Anglo-Zulu War of 1879—which included the Battle of Isandlwana and the Battle of Rorke's Drift—as well as during the Sudanese Campaign of 1884–1898, and in various other colonial conflicts in Africa and India.
After initial victories, such as the Battle of Isandlwana, the British repeatedly defeated the Zulu armies in the field before finally capturing the Zulu capital at the Battle of Ulundi.
He outmanoeuvred Lt. Gen. Lord Chelmsford, diverting part of the British force, then defeating and annihilating the encamped British Army at the Battle of Isandlwana, after the epic battle he became Britain's biggest foe.