Berbérati is served by the Berbérati Airport and is often visited by tourists on their way to the Dzanga-Sangha Special Reserve.
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In 1911 it was ceded to German Empire under the terms of the Morocco–Congo Treaty and Treaty of Fez, becoming part of the German colony of Neukamerun, until it was reconquered by the French in 1916 following the defeat of German forces in western Africa during World War I.
Production of gold and diamonds, which is mostly artisanal, comes from the regions of Berberati, Haute-Kotto, and Haute-Sangha.
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Other companies exploring for diamond included Pangea Diamondfields Plc (Isle of Man), which planned to invest $3.2 million in a bulk sampling plant for its Dimbi (Basse-Kotto) project concession area, and Gem Diamonds Ltd. (UK), which held exploration and mining permits for the Mambéré river project near the city of Berberati.