Reagon was an active participant in the Black Civil Rights Movement of the 1960s as a member of The Freedom Singers, organized by the Student Non-violent Coordinating Committee (SNCC).
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She was a teacher and mentor to the young people of SNCC, highly influencing the thinking of such important figures as Julian Bond, Diane Nash, Stokely Carmichael, Curtis Muhammad, Bob Moses, and Bernice Johnson Reagon, who wrote a song in Baker's honor, called "Ella's Song".
She is the daughter of Freedom Singers co-founders Dr. Bernice Johnson Reagon, founder of Sweet Honey in the Rock, with whom she has sometimes collaborated on musical projects and of Cordell Hull Reagon, a leader of the civil rights movement in Albany, member of the Student Nonviolent Coordinating Committee (SNCC), and co-founder of The Freedom Singers.