In a Phase I clinical trial conducted in 2009–2010, John A. Boockvar's team at Weill Cornell Medical College administered bevacizumab intra-arterially directly into the brain tumors of fourteen patients with recurrent glioblastoma multiforme.
On November 3, 2010, The New York Times reported that Genentech began offering secret rebates to about 300 ophthalmologists in an apparent inducement to get them to use more ranibizumab rather than their less expensive bevacizumab.