The Chinese Buddhist monk Xuanzang visited a Mahāsāṃghika monastery at Bamiyan, Afghanistan, in the 7th century CE, and the site of this monastery has been rediscovered by archaeologists.
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There are several other mantras for the Medicine Buddha as well that are used in different schools of Vajrayana Buddhism.
The most important Nyorai of the Japanese Buddhist pantheon (apart from the historical Buddha, Shaka Nyorai) are Amida Nyorai (Amitābha), Dainichi (or Birushanabutsu) Nyorai (Vairocana), and Yakushi Nyorai (Bhaisajyaguru).
The main object of veneration, Yakushi Nyorai, also named "The Medicine Buddha", was one of first Buddhist Deities to arrive in Japan from China in 680, and gives the temple its name.