As Biffo was the cover star at the time, and Buster's name was never in the title, this must be from The Beano Book 1957, not an issue of the comic.
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More recently Biffo was seen in a four-part special leading a group of retired characters, Pansy Potter, Keyhole Kate and Desert Island Dick, to return The Beano to an earlier form (specifically, the 1960s, the logo from that era was used in the story).
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As the issue was edited by Nick Park (creator of Wallace and Gromit), animals in the zoo could be seen that bore a close resemblance to that of his 1989 short film, Creature Comforts.
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These strips were mostly drawn by Sid Burgon, though Trevor Metcalfe contributed a few stories as well, including in the Beano Book 1994.
Bear | bear | Bear Bryant | American black bear | Bear Stearns | Yogi Bear | Grizzly Bear | Greg Bear | Big Bear | Paddington Bear | Smokey Bear | Bear Grylls | American Black Bear | White Bear Lake, Minnesota | Great Bear Lake | Build-A-Bear Workshop | Rupert Bear | Elizabeth Bear | Big Bear Lake | White Bear Lake | Grizzly bear | Boy & Bear | black bear | Sitting Bear | Fozzie Bear | Brother Bear | Bear Shooters | White Bear Township, Ramsey County, Minnesota | White Bear Township | Running Bear |