The conflict is between the invading Orks under the leadership of the Ork Warlord Ghazghkull Mag Uruk Thraka and the Imperial world of Armageddon's defence forces under the joint command of Herman von Strab, Overlord of Armageddon; Commander Dante of the Blood Angels; and Imperial Commissar Yarrick.
Set in the Warhammer 40,000 universe, it is effectively a 'scaled-down' version of Space Hulk and Tyranid Attack, using plastic Marine Scouts from the Ultramarines, Space Wolves, Dark Angels and Blood Angels chapters.
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