Santiago Alba y Bonifaz (1872–1949), Spanish politician, lawyer, and politician
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Ramón de Bonifaz (1196-1252 or 1256), medieval Spanish naval leader
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John Bonifaz (born 1966), Boston-based attorney and political activist
Cristóbal Bonifaz, founder member of the Charles Darwin Foundation, Diego Bonifaz, a former Mayor of Cayambe during 2000-2011 period, and Rafael Bonifaz, former Elastix distro community manager.