X-Nico

2 unusual facts about CFHR5


Alternative complement pathway

CFHR5 (Complement Factor H-Related protein 5) is able to bind to act as a cofactor for factor I, has decay accelerating activity and is able to bind preferentially to C3b at host surfaces.

CFHR5 nephropathy

Complement factor H-related protein 5 (CFHR5) nephropathy (also known as Troodos nephropathy) is a form of inherited kidney disease which is endemic in Cyprus and is caused by a mutation in the gene CFHR5.


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CFHR5 |


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