As the leader of the Cure Alzheimer’s Fund Alzheimer’s Genome Project, Dr. Tanzi has carried out multiple genome wide association studies of thousands of Alzheimer’s families leading to the identification of novel AD candidate genes, including CD33 and the first two rare mutations causing late-onset AD in the ADAM10 gene.
gene | Gene Autry | Gene Hackman | Gene Roddenberry | Gene Simmons | Gene Kelly | Gene Pitney | Gene Krupa | The Manchurian Candidate | Gene Watson | Candidate of Sciences | Gene Wilder | Gene Tunney | gene expression | Gene Eugene | Officer Candidate School | Gene Tierney | Gene Robinson | Gene Raymond | Gene expression | Gene Deitch | Gene Clark | Gene | tumor suppressor gene | Gene Wolfe | Gene Summers | Gene Lees | Gene Harris | Gene Fullmer | Gene Ammons |
In molecular biology, the Btz domain (CASC3/Barentsz eIF4AIII binding domain) is a protein domain found on CASC3 (cancer susceptibility candidate gene 3 protein) which is also known as Barentsz (Btz).
The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene.
This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature.