Completed in 1914, it is the mother church of the Archdiocese of St. Louis and the seat of its archbishop, currently Robert James Carlson.
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In 1999, a 14-foot high, welded stainless steel sculpture by Wiktor Szostalo was installed on the side lawn of the church.
Then-Archbishop Raymond Leo Burke of the Archdiocese of St. Louis ordained two American priests in the United States for the first time at the Cathedral Basilica of Saint Louis, Missouri on the feast day of the Most Sacred Heart of Jesus, June 15, 2007.
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