Ergotamine is a secondary metabolite (natural product) and the principal alkaloid produced by the ergot fungus, Claviceps purpurea, and related fungi in the family Clavicipitaceae.
Epichloë species and their close relatives, the Neotyphodium species, are systemic and constitutive symbionts of cool-season grasses (Poaceae subfamily Pooideae), and belong to the fungal family Clavicipitaceae.