Poyle is a largely industrial and agricultural area in the unitary authority of Slough, England, adjoining the Colne Valley regional park.
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On leaving the Colne at Uxbridge Moor in the Colne Valley regional park, the Colne Brook flows close by to the west until West Drayton then passes under the M25 motorway at the M4 "Thorney interchange", enters Berkshire and flows through the village of Colnbrook.