Big Cyc |
Doug Lenat's Cyc project, one of the oldest and most ambitious projects to capture all of human knowledge in machine readable form, is "a determinedly scruffy enterprise" (according to Pamela McCorduck).
CLOCK (circadian locomotor output cycles kaput) was first cloned in mouse and BMAL1 (brain and muscle aryl hydrocarbon receptor nuclear translocator (ARNT)-like 1) is the primary homolog of Drosophila CYC.