The main function of this domain is the inhibition of DFFB by binding to its C-terminal catalytic domain through ionic interactions, thereby inhibiting the fragmentation of DNA in the apoptotic process.
DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits.
Gian-Piero Ringel studied film production at the Deutsche Film- und Fernsehakademie Berlin (dffb).
From 1976-81 Michael Meert studied at the German Film and Television Academy Berlin (dffb), where he met Andrei Tarkovsky, Joris Ivens and Johan van der Keuken.