After saving Bay City from nuclear annihilation at the hands of the Soviets, Crypto discovers that the KGB have fled to Albion and promptly follows, where he meets Reginald Ponsonby-Smythe, the James Bond-esque head of M16 (a parody of MI6), and a rogue KGB agent named Natalya Ivanova.
Destroy All Humans! 2 (Lakeshore Records, 2006) — contributed "Straight Thru You"
Sunrise: A Song of Two Humans | Destroy Rock & Roll | Destroy All Monsters | Destroy All Humans! | Like Humans Do | Recent African origin of modern humans | Effects of high altitude on humans | Destroy What You Enjoy | Destroy the Runner | Destroy The Children | Destroy Rebuild Until God Shows | Destroy All Monsters (band) | Destroy All Humans! 2 | block and fortify the country's western borders - and to destroy several adjacent villages in the process |
It also is a major theme in the game Destroy All Humans!, largely as an intentional music joke as the video game is set in 1957, nine years before the song's release.
A remix of their version of the song "Sh-Boom" was featured in the credits of the video game Destroy All Humans!.
The movie was included as an extra on the 2005 PS2 video game Destroy All Humans!.