Each germ asserted their plans to inflict suffering, sometimes in parody of well known films such as The Godfather, before being wiped out by a specific brand of Domestos.
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During the late 1980s and early 1990s, Domestos marketing campaign featured a mock of a scene from the film Big Bad John in which a Domestos bottle moved slowly around a bathroom in the style of a cowboy as nearby loo brushes and ornaments hid nervously.
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In 2005, various commercials for different Domestos brands were shown on British television, with computer generated germs made to represent Salmonella, E.Coli and Staphylococcus.
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The commercial ends with a voiceover of the slogan, read by famous British actor Patrick Stewart.