From April 22–23, 2006, Yamamoto met with current Chadian President Idriss Déby to discuss Chad's dispute with the World Bank over allocation of its petroleum funds and the possibility of a U.S.-led, United Nations-monitored peace keeping force to end the Chadian-Sudanese conflict.
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Yamamoto met with Ethiopian Prime Minister Meles Zenawi on April 22, 2006, to discuss the ongoing process of democratization in Ethiopia and the Ethio-Eritrea boundary dispute.
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Yamamoto became acting Assistant Secretary of State for African Affairs on March 30, 2013, replacing Johnnie Carson.
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Note: Vicki J. Huddleston served as the Chargé d'Affaires ad interim at the embassy in Addis Ababa until Donald Yamamoto became the ambassador.