At the ventral end of the embryo, blastoderm nuclei exposed to high concentrations of dorsal protein induce the transcription of the transcription factors twist and snail while repressing zerknüllt and decapentaplegic.
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It has been shown that the dsRNA-binding protein STAUFEN (STAU1) is responsible for guiding bicoid, nanos and other proteins, which play a role in forming the anterior-posterior axis, to the correct regions of the embryo to build gradients.
Drosophila melanogaster | Drosophila | Drosophila pseudoobscura | Embryogenesis | Drosophila simulans | drosophila |