Attempts were made by Thomas Radclyffe, 3rd Earl of Sussex, Lord Lieutenant of Ireland, to expel the MacDonnells back to Scotland.
During the Northern Rebellion of 1569, George was knighted in the field by the Earl of Sussex for bravery.
Henry Radclyffe, 2nd Earl of Sussex, KG (also spelled "Radcliffe") (1507 – 17 February 1557) was a son of Robert Radclyffe, 1st Earl of Sussex and his wife Elizabeth Stafford, Countess of Sussex.
It was a possible Saxon royal minster of Benedictine nuns and was founded or refounded about 1082AD by Roger de Montgomery, Earl of Sussex, who granted land to St. Peter's Abbey, Almenesches.
The Lord Deputy of Ireland, the Earl of Sussex, ordered that they be dispossessed and replaced with an English settlement.
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Although originally built by the Earl of Shrewsbury, the Earls of Sussex owned the castle in the period 1154–1176, after which it passed into possession of the Crown.
By way of retaliation the English, under the Earl of Sussex and Lord Scrope, destroyed his stronghold at Branxholme Castle.
He succeeded to the title on the death of his father, on 10 December 1559, and during his minority was the ward of Thomas Ratcliffe, third earl of Sussex, for whom he conceived a great friendship.
Henry Radclyffe, 2nd Earl of Sussex (1507 - 1557), son of Robert Radclyffe, 1st Earl of Sussex and Elizabeth Stafford, Countess of Sussex