Edward le Despencer, 1st Baron le Despencer, KG (also called Despenser) (c. 24 March 1335 or 1336 – 11 November 1375) was the son of another Edward le Despenser and Anne, the sister of Henry, Lord Ferrers of Groby.
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Constance of York (c.1374 – 28 November 1416), who married Thomas le Despenser, 1st Earl of Gloucester (22 September 1373 – 16 January 1400), third but first surviving son of Edward le Despenser and Elizabeth Burghersh, by whom she had a son, Richard, and two daughters, Elizabeth and Isabel.