By measuring the currents activated in excised inside-out membrane patches upon superfusion with varying ligand concentrations, the ligand sensitivity and selectivity of both endogenously and exogenously expressed CNG channels have been studied.
Classical or serotonergic psychedelics (agonists for the LSD (also known as "acid"), psilocin (the active constituent of psilocybin mushrooms, commonly known as "magic mushrooms" or "shrooms"), mescaline (the active constituent of peyote), and DMT (the active constituent of ayahuasca and potentially an endogenous psychedelic compound).
Endogeny |