It lies on the railway between Tunis and Sousse, approximately 45 km northeast of Sousse and a few kilometres inland from the Gulf of Hammamet.
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Enfidaville became the chief settlement on the Enfida estate, a property of over 300,000 acres (1,200 km²) in the Sahel district of Tunisia, forming a rectangle between the towns of Hammamet, Sousse (Susa), Kairawan and Zaghwan.