He made his formal debut in the summer of 1959, as the Chevalier des Grieux in Jules Massenet's Manon, with The Experimental Opera Theatre of America (affiliated with the New Orleans Opera Association), conducted by Renato Cellini and directed by Armando Agnini.
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Outside of the US, Di Giuseppe made appearances with Ottawa Opera, the Canadian Opera Company, Vancouver Opera, and the Palacio de Bellas Artes in Mexico City.
Enrico Caruso | Giuseppe Garibaldi | Enrico Fermi | Giuseppe Tornatore | Enrico Ferri | Giuseppe Sinopoli | Giuseppe De Santis | Giuseppe Capogrossi | Giuseppe Terragni | Giuseppe Mazzini | Enrico Macias | Enrico Baj | Giuseppe Ungaretti | Giuseppe Lignano | Giuseppe Tucci | Giuseppe Radaelli | Giuseppe Pizzardo | Giuseppe Morello | Giuseppe Marchese | Giuseppe Guarneri | Giuseppe Di Cristina | Enrico Cialdini | Enrico Castellani | San Giuseppe Jato | Robert Enrico | Rima San Giuseppe | Giuseppe Valdengo | Giuseppe Tomasi di Lampedusa | Giuseppe Soleri | Giuseppe Sergi |