Epistasis refers to genetic interactions in which the mutation of one gene masks the phenotypic effects of a mutation at another locus.
Epistasis: when the alleles at one locus change the phenotypic effects of genetic variation at another locus, the two genes are said to exhibit 'epistasis' in their interactions.
Epistasis - the collective action of multiple genes that interact during expression.
This reflects all the genetic contributions to a population's phenotypic variance including additive, dominant, and epistatic (multi-genic interactions), as well as maternal and paternal effects, where individuals are directly affected by their parents' phenotype (such as with milk production in mammals).
The frame overo gene can be masked by other white patterns, particularly tobiano, which is a dominant gene and epistatic to overo.
Another cause arises from the interaction between two alleles, also known as the epistatic effect between alleles.
Solid-white Turkish angoras carry the epistatic (masking) white colour (W) dominant gene associated with white fur, blue eyes and often deafness.