The Exploding Plastic Inevitable, sometimes simply called Plastic Inevitable or EPI, was a series of multimedia events organized by Andy Warhol between 1966 and 1967, featuring musical performances by The Velvet Underground and Nico, screenings of Warhol's films, and dancing and performances by regulars of Warhol's Factory, especially Mary Woronov and Gerard Malanga.
Originally intended for Nico to sing (who did indeed sing it on a few occasions during the Exploding Plastic Inevitable shows), the song was demoed in 1967 by Lou Reed, Sterling Morrison and John Cale.
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According to the Unsound website, the "series refers to Warhol’s own extensive use of pre-existing material to create something new, as well as the 60s multimedia event The Exploding Plastic Inevitable, which used Warhol’s film work as moving wallpaper projected onto a wall and musicians from The Velvet Underground."
During that time, as Cutrone worked with Warhol on paintings, prints, films, and concepts, he hit upon the style the critics called "Post-Pop." And, along with Mary Woronov and Gerard Malanga, danced onstage with the Velvet Underground and Nico as part of the Exploding Plastic Inevitable show.