It was first isolated and purified by Brazilian scientist José Moura Gonçalves, and later intensively studied by his group of collaborators at the Medical School of Ribeirão Preto of the University of São Paulo (C.R. Laure, A. Haddad, F.L. De Lucca and J.R. Giglio, among others).
Ribeirão Preto | Faculdade de Medicina de Ribeirão Preto | Ouro Preto | Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa | São José do Rio Preto | Rio Preto da Eva | Universidade Federal de Ouro Preto | Rio Preto | Ribeirão das Neves | Instituto de Medicina Molecular | Faculdade de Engenharia da Universidade do Porto | Faculdade de Direito do Recife |
It is affiliated to the Medical School of Ribeirão Preto.
In that year, Rocha e Silva was invited to be the chairman of the Department of Pharmacology of the recently created Faculty of Medicine of Ribeirão Preto of the University of São Paulo, in the city of Ribeirão Preto, state of São Paulo, a position he held until his mandatory retirement in 1980.