In 2006, Anna Karen used her experience as a striptease dancer to act as a judge in the final edition of Channel 4's reality television documentary Faking It.
Her film and television appearances include The Brenda and Glennda Show; To Wong Foo, Thanks for Everything! Julie Newmar; HBO's Dragtime; TLC's Faking It; Wigstock, The Movie; Project Runway; and Sex and the City.