Francis I accorded him a warm reception and gave him the Abbey of St. Benignus at Dijon.
Ottaviano and Federigo Fregoso are participants in the fictional discussion presided over by Elisabetta Gonzaga, Duchess of Urbino, in Baldassare Castiglione's The Book of the Courtier, which was supposed to have taken place at the court of Urbino in 1507.