In this period ambitious players explored the Ruy Lopez, believing it a better attempt for White to exploit the advantage of the first move.
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Black's most common reply is 2...Nc6, which usually leads to the Ruy Lopez (3.Bb5), Italian Game (3.Bc4), or Scotch Game (3.d4), though 3.Nc3 Nf6 (the Four Knights Game), often played in the late 19th to early 20th century, or, less commonly, 3....g6, (the Three Knights Game), are other possibilities.