Born in Buffalo, New York, Striker attended Lafayette High School and the University of Buffalo, where he was a member of the Theta Chi Fraternity.
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In Detroit, James Lipton portrayed the Lone Ranger's nephew, Dan Reid, during the early 1940s.
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He began a long association with station owner George W. Trendle and radio station WXYZ in Detroit, which was trying to make a name for itself as a producer of radio drama, creating and writing the early series Thrills of the Secret Service, Dr. Fang, and Warner Lester, Manhunter (which introduced Mike Axford, later a supporting character on The Green Hornet).
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In 1929, he moved to WTAM in Cleveland, Ohio, where he served as announcer and continuity writer and wrote his first radio drama script, a biography of Stephen Foster.
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