Shattuck was instrumental in getting the Central Pacific Railroad to construct a branch line into Berkeley in 1876 connecting the community and University of California with the main line and the railroad's ferry to San Francisco.
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The principal avenue in the city of Berkeley, Shattuck Avenue, is named for him, as is a smaller street, Kittredge.
Shattuck Hotel or Hotel Shattuck Plaza, located in Downtown Berkeley, was opened in December 1910 with the consent of Rosa Shattuck, wife of prominent gold seeker and builder Francis K. Shattuck, .
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On 27 February 1994, Wei met with United States Assistant Secretary of State for Human Rights John H. Shattuck to discuss human rights conditions in China, and also met with journalists.