His nickname, "Chance," came from being compared to the Chicago Cubs' first baseman, Frank Chance.
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With the Cubs, he created the famous Tinker to Evers to Chance infield combination, by converting Frank Chance from catcher to first base, Joe Tinker from third base to shortstop, and Johnny Evers from shortstop to second base.
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After he left Boston, he went on to manage in Chicago where built the basis for the Cubs' later success by signing and utilizing the talents of Frank Chance, Joe Tinker, and Johnny Evers.