The earliest fully documented case of aortic dissection is attributed to Frank Nicholls in his autopsy report of King George II of Great Britain, who had been found dead on 25 October 1760; the report describes dissection of the aortic arch and into the pericardium.
He attended some of Winslow's lectures in France, and saw Giovanni Battista Morgagni and Santorinus in Italy; and on his return began to give anatomical lectures in London.
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