1739 (Genbun 4): Hosokawa Etchū-no-kami of Higo was killed in Edo castle by Itakura Katsukane, and the killer was ordered to commit suicide as just punishment; however, Shogun Yoshimune personally intervened to mitigate the adverse consequences for the killer's fudai family.
In the Bakumatsu period, Nagayuki served as a Rōjū in the government, and Karatsu domain itself was a Fudai domain, unlike the neighboring Nabashima domains, which were of Tozama domain status.