The series is directed by Yoshiyuki Fujiwara at studio Dogakobo with script by Fumihiko Shimo and character design by Ai Kikuchi, who is also the chief animation director.
Enterbrain published two volumes of a light novel series titled Photo Kano: Pentaprism Memories, written by Fumihiko Shimo and illustrated by Natsume Shimano, between March and June 2012.
A novelization of Rosario + Vampire written by Fumihiko Shimo was released by Shueisha on April 4, 2008 under their Jump j-Books imprint.