Clockwise, it follows the southern shore of Hangzhou Bay to Hangzhou, where it turns north and becomes concurrent with G60 Shanghai–Kunming Expressway and G2501 Hangzhou Ring Expressway.
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At this interchange, the extra, non-orbital section of expressway to Shanghai branches off to the north while the orbital continues to the south and crosses the bay using the Hangzhou Bay Bridge.
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The expressway continues eastward, following the north shore of Hangzhou Bay until it reaches an interchange with the S11 Zhapu–Jiaxing–Suzhou Expressway and the G15 Shenyang–Haikou Expressway in Jiaxing.
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